The concept of “human factor” is actively used in determining the guilt of pilots in plane crashes and drivers in railway accidents, as well as from a historical perspective, in economics and management of organizations, but surprisingly rarely when it comes to road transport. In addition, the human factor usually means the driver’s fault, which is the main misconception. Other causes of road accidents include weather conditions, the state of the road infrastructure, and technical malfunctions, hiding the true cause, which in the vast majority of cases is also a consequence of human factors of various levels. An analysis of incidents with buses and trucks that regularly occur in Russia shows that it is possible to distinguish such levels of human factor as driver, managerial, political, legal, technological, production, system, and commercial. A bus or heavy truck accident is always fraught with particularly serious consequences and public outcry. However, public outcry does not yet mean that the authorities will take the necessary steps in this direction in terms of organizing transportation processes and monitoring motor transport enterprises. Therefore, it is necessary to invent technical solutions, including an integral brake valve, a driver monitoring system and a post-accident braking system.